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缪文俊
阅读次数:发布时间:2023-05-25

缪文俊,教授,硕士生导师药学院副院长。

主要从事面向恶性肿瘤、耐药病原体诊断与治疗的光学活性药物、新型给药系统的应用基础研究,发表高水平SCI论文三十余篇;主持国家重点研发计划生物安全重大专项和国家自然科学基金等科研项目五项,入选江苏省“六大人才高峰”和“双创博士”项目,“南工青年英才”创新生物医药团队负责人;入选中国药学会、中国微循环协会专委会委员、青年委员,多个SCI期刊编委等。

教育经历:

首尔大学,药学院药学专业,博士

苏州大学,药学院药剂学系,硕士

苏州大学,药学院药学系,学士

科研与学术工作经历:

新利18彩票 ,药学院,副教授、教授

韩国科学技术研究院(KAIST),博士后

主持科研项目(课题)情况:

1.国家重点研发计划生物安全重点专项课题(2016YFC1201504),消毒灭菌关键设备的研制,课题负责人

2.国家自然科学基金青年基金,面向恶性黑色素瘤诊疗的新型近红外光响应性多功能纳米载体的研究,51603101,项目负责人

3.江苏省高校自然科学计划面上项目,近红外光响应型多功能纳米载体的构建及其抗肿瘤的研究,16KJB350001,项目负责人

代表性研究论文

[1]Rongrong Huang, Lei He, Lian Jin*, Zhiyang Li, Nongyue He*,WenjunMiao*.Recent advancements in DNA nanotechnology-enabled extracellular vesicles detection and diagnosis: A mini review.Chinese Chemical Letters, 2023, 34, 107926. https://doi.org/10.1016/j.cclet.2022.107926

[2] Yangye Jin, Cong Wang, Ziyan Xia, Peiyuan Niu, Yuanyuan Li,Wenjun Miao*. Photodynamic chitosan sponges with dual instant and enduring bactericidal potency for treating skin abscesses. Carbohydrate Polymers. 2023, 306, 120589. https://doi.org/10.1016/j.carbpol.2023.120589

[3] Xiaofeng He, Wenjing Guo, Yuxuan Tang, Jianming Xiong, Yuanyuan Li, Rongrong Huang,Wenjun Miao*. Chloroplastboosted photodynamic therapy for effective drug-resistant bacteria killing and biofilm ablation.Journal of Photochemistry & Photobiology, B: Biology,2023, 238, 112622. https://doi.org/10.1016/j.jphotobiol.2022.112622(本科生一作,SCI二区)

[4] Zeyu Fan, Yuxin Guo, Xinrui Gu, Rongrong Huang*,Wenjun Miao*.Development and validation of an artificial neural network model for noninvasive gastric cancer screening and diagnosis. Scientific Reports.2022, 12, 21795. https://doi.org/10.1038/s41598-022-26477-4

[5] Yuanyuan Li, Jianming Xiong, Yi Hu,Wenjun Miao*, He Huang*. Wrapping collagen-based nanoparticle with macrophage membrane for treating multidrug-resistant bacterial infection.Journal of Leather Science and Technology,2022, (4)31:1-12. https://doi.org/10.1186/s42825-022-00106-2

[6] Wenjing Guo, Yuanyuan Li, Daoguang An, Min Zhou, Jianming Xiong, Zhijun Jiang, Yimei Ding, Rongrong Huang*,Wenjun Miao*. Sodium ferulate-functionalized silver nanopyramides with synergistic antithrombotic activity for thromboprophylaxis.Colloids and Surfaces B: Biointerfaces,2022, 220, 112925

[7] Yuanyuan Li, Xiaolong Li, Jie Yu, Zheng Wan , Yi Hu, Rongrong Huang, Youtian Tao * ,Wenjun Miao*. A versatile diketopyrrolopyrrole-based photosensitizing nanoplatform with high photostability and photoactivity for metastatic breast cancer treatment.Dyes and Pigments, 2022, 207, 110748. https://doi.org/10.1016/j.dyepig.2022.110748(一区,通讯作者)

[8] Yangye Jin, Binbing Zhao, Wenjing Guo, Yuanyuan Li, Juncheng Min,Wenjun Miao*. Penetration and photodynamic ablation of drug-resistant biofilm by cationic Iron oxide nanoparticles.Journal of Controlled Release, 2022, 348:911-923.https://doi.org/10.1016/j.jconrel.2022.06.038(一区,通讯作者)

[9] Yuanyuan Li, Yangye Jin, Xiaofeng He, Yonghui Tang*, Min Zhou, Wenjing Guo,Wenjun Miao*.Cyclo(RGD) peptide-decorated silver nanoparticles with anti-platelet potential for active platelet-rich thrombus targeting.Nanomedicine: Nanotechnology, Biology, and Medicine, 2022, 41, 102520. https://doi.org/10.1016/j.nano.2022.102520(二区,通讯作者)

[10] Yuanyuan Li, Aiyang Tong, Peiyuan Niu, Wenjing Guo, Yangye Jin, Yi Hu, Pei Tao,Wenjun Miao*.Light-Decomposable Polymeric Micelles with Hypoxia-Enhanced Phototherapeutic Efficacy for Combating Metastatic Breast Cancer.Pharmaceutics, 2022, 14, 253. https://doi.org/10.3390/pharmaceutics14020253(二区,通讯作者)

[11] Peiyuan Ni, Jialing Dai, Zeyu Wang, Yueying Wang, Duxiang Feng, Yuanyuan Li *,Wenjun Miao *.Sensitization of Antibiotic-Resistant Gram-Negative Bacteria to Photodynamic Therapy via Perfluorocarbon Nanoemulsion.Pharmaceuticals, 2022, 15, 156. https://doi.org/10.3390/ph15020156(本科生一作,SCI三区)

[12]Yuanyuan Li, Jianming Xiong, Wenjun Miao*, He Huang*. Decomposable black phosphorus nano-assembly for controlled delivery of cisplatin and inhibition of breast cancer metastasis. Journal of Controlled Release, 2021, 335,:59-74.(一区,通讯作者)

[13] Jingyi Zhu, Jinhua Zhao*,Wenjun Miao*.131I-Labeled Multifunctional Polyethylenimine /Doxorubicin Complexes with pH-Controlled Cellular Uptake Property for Enhanced SPECT Imaging and Chemo/Radiotherapy of Tumors.International Journal of Nanomedicine. 2021, 16:5167-5183. (二区,通讯作者)

[14]Yuanyuan Li, Pengcheng Feng, Cong Wang,Wenjun Miao*, He Huang*. Black Phosphorus Nanophototherapeutics with Enhanced Stability and Safety for Breast Cancer Treatment.Chemical Engineering Journal.2020, 400, 125851. (一区,通讯作者)

[15]Ronglu Zhang, Yuanyuan Li, Min Zhou, Cong Wang, Pengcheng Feng,Wenjun Miao*,He Huang*. Photodynamic Chitosan Nano-Assembly as a Potent Alternative Candidate for Combating Antibiotic-Resistant Bacteria.ACS Appl. Mater. Interfaces2019, 11, 30, 26711-26721. (二区,通讯作者)

[16]Yuanyuan Li,Wenjun Miao*,He Huang*. Highly stable and biocompatible nanocontrast agent encapsulating a novel organic fluorescent dye for enhanced cellular imaging,Powder Technology2019, 35815,110-119. (二区,通讯作者)

[17]Wenjun Miao*,Gayong Shim*,Seungbum Ko , Kyu Thae Park , Jinyoung Kim , M. G. Kim , Young Bong Kim and Yu-Kyoung Oh. Immune-camouflaged graphene oxide nanosheets for negative regulation of phagocytosis by macrophages.J. Mater. Chem. B,2017, 5, 6666-6675.

[18]Wenjun Miao,Hyungjun Kim, Vipul Gujrati, Jin Yong Kim, Hyeongsu Jon, Yonghyun Lee, Minsuk Choi, Jinjoo Kim, Soyoung Lee, Dong Yun Lee, Sukmo Kang, Sangyong Jon*. Photo-decomposable Organic Nanoparticles for Combined Tumor Optical Imaging and Multiple Phototherapies.Theranostics, 2016, 6(13):2367–2379. (一区,一作)

[19]Wenjun Miao,Gayong Shim, Gonwoo Kim, Soondong Lee, Hee-Jung Lee, Young Bong Kim, Youngro Byun, Yu-Kyoung Oh*.Image-guided synergistic photothermal therapy using photoresponsive imaging agent-loaded graphene-based nanosheets.J Control Release, 2015, 211, 28-36.(一区,一作)

[20]Wenjun Miao, Gayong Shim, Soondong Lee, Yu-Kyoung Oh*.Structure-dependent photothermal anticancer effects of carbon-based photoresponsive nanomaterials.Biomaterials, 2014, 35, 4058-4065.(一区,一作)

[21]Wenjun Miao, Gayong Shim, Choong Mo Kang, Soondong Lee, Yearn Seong Choe, Han-Gon Choi, Yu-Kyoung Oh*. Cholesteryl hyaluronic acid-coated, reduced graphene oxide nanosheets for anti-cancer drug delivery.Biomaterials, 2013, 34, 9638-9647.(一区,一作)

[22]Wenjun Miao, Gayong Shim, Sangbin Lee, Soondong Lee, Yearn Seong Choe, Yu-Kyoung Oh*. Safety and tumor tissue accumulation of pegylated graphene oxide nanosheets for co-delivery of anticancer drug and photosensitizer.Biomaterials, 2013, 34, 3402-3410. (一区,一作)

E-mail:miaowj@njtech.edu.cn

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